Friday 31 May 2013

Swelle Review: Fashion and Beauty Apps - The Swelle Life

Net_2

I've been a little slow getting in on the app game despite having an iPad2 for at least two years now;?maybe it's because I pretty much only used the iPad to play Ms. PacMan (which my husband put on knowing that would be my first priority because I'm awesome at it - don't laugh!), and I work from home so I'm on my laptop all day and tend to use websites since that's what's in front of me.?

But it was time I got onto exploring the universe of apps available to us through our devices, it got?embarrassing having to shake my head 'no' when asked if I know this one or that one, then having to explain that I am actually otherwise clued into the online world, I work strictly with digital media for a living! So, when browsing mobile phones on the web?to find out what the current upgrade on my phone looks like, I came across some fashion and beauty apps and decided to put in some time seeing what clever things are out there.?

In terms of shopping, clearly I like Net-a-porter. They are the pioneers of online luxury shopping and became the model to follow in terms of website design and product presentation, and they've also got a fantastic online magazine. So I was curious how all of this web greatness translates on an Android mobile phone, specifically the HTC Sensation which is what I use.?

This is what the homepage of the app looks like (images are screencaps from Net-a-porter's video):

Net_1

The landing page automatically opens on the Shop tab from which you can select 'What's New', browse the designer directory and product categories, or see a curated grouping of products via the 'Trend Edit' option. Or you can select the News tab which appears to be the mobile version of their digital magazine, Edit which features brilliantly shot editorial - you can always shop the shoot directly from the page because, of course, everything featured is from Net-a-porter - as well as interviews and trend stories. And also from the front page is a 'Live' option which is something exclusive to the app, and something that took me a few seconds to figure out. 'Why is it showing me products and telling me that they've been added to so-and-so's shopping bag or wish list?' Ah, ok, this is the social aspect worked in. I probably wouldn't browse this feature again, but I am aware that some others would be interested in being influenced by others' choices and so I can see its relevance in a shopping app (as you probably already know, there are shopping apps and websites based entirely on this principle, one of which is coming up). And I suppose it can bring items to your attention that we may not otherwise come across in the vast yet discerning?sea that is Net's product offering.?

Net_3

Since the primary purpose of the app is shopping, I tried to buy an item (stopping short of the actual purchase, unfortunately!) to see how the selection process and shopping cart function compares to the smoothness of the website. I selected the 'Shoes' category from the homepage which went to the 'Shoes Type' page where you can select the style you want to look at or just go with 'All Shoes' which is what I did. Then I decided I wanted to see what Esquivel shoes they currently have (my favourite) and to do that I returned to the homepage by hitting 'Net-a-porter' in the top left corner of the screen and found the brand in the Designer A-Z page. It gave me four style options, and I clicked on red brogues with a white detail that has a spray-painted effect because they were screaming for my attention. I ran into a few glitches with the images. I got 'image not available' a few times and as I scrolled through was able to see other shots rather randomly. The first three looked low-res whereas the remaining four were crisp. I wondered for a second how you buy the item and tried pulling up a menu from the bottom I hoped was there, and it was. From this menu you can select to view each of the details you get from the product page view on the website. But I couldn't figure out how to add it to the cart. Trying to conjure an 'add' feature with my finger wasn't working, but after staring at the screen for longer than I'd care to admit, I noticed a + button in the top right corner. I hit it and was given the option to add the shoes to the shopping bag or wish list. I selected 'shopping bag' and a list of sizes dropped down. I went for my Esquivel size which is US 7 and then it showed me my selection with the total and a button to confirm the purchase. I didn't do that since I wasn't actually buying them (nuts!) but I'd assume the purchase would have been successful. I should mention that I browsed quite a few other products and didn't find any image problems with those - everything loaded and looked high-res, so I went back to look at the Esquivels again and guess what, all images loaded and were crisp so it was probably that the images hadn't fully loaded although I did give it some time. I put that down to my phone, not the app.?

My overall impression: A smooth and comprehensive app that represents the aesthetic and features of the website well and delivers a similar feel and experience. My one suggestion would be to make the 'add to bag' or 'add to wish list' function more obvious to avoid missing it altogether and abandoning the app in frustration, and ultimately feeling like a dumkopf with no new gear on its way. (Unless this is how all shopping apps work, in which case you can just ignore that last part!)

The Net-a-porter app is free and available for iPad, iPhone and Android in English, French, German and simplified Chinese versions. You can find out more about the app and download it?here?

Pose

Pose is an online and mobile fashion community that has been generating a lot of media buzz and has been called 'The Instagram of Fashion'. There are dozens of sites like it as developers are capitalising on the current hunger for social engagement, fashion show and tells, and the compulsion to buy something right NOW! that looked really hot on a girl who lives in a country that seems so much cooler than your own. Social influence is driving purchasing decisions and the cool kids have it. The developers attract the fashionistas who attract more users who will probably buy something at some point, and they tell their friends about it, and so on.?

So I was curious to see what I might get out of it, if anything. For this one I decided to use the iPad2 since the app is image heavy and it's not available for Android anyway. To begin, I had to create an account. I used my email and then was allowed entry. It told me 'Pose is where fashion happens...and you're about to see why.' Ok! Hmm...now it wants me to take a quiz so they can suggest the best people on Pose for me to follow. Can I bypass this? I instantly resent anything that tries to pigeonhole me - I'm a varied and complex individual! And so are you. Oh well. Here we go. I guess it's just trying to make the sea of fashion more digestible and relevant, although it makes me wonder what I'm not being shown. You can skip questions but at the end it automatically chooses people for you to follow. It gave me four users, incuding Rachel Zoe and Coco Rocha. Something tells me that was not random. Next you can create 'collections' to save 'poses' for inspiration, to buy, or to share with your friends. I hit 'stream' and was brought to a page showing me the poses from people I follow, you know, those four I didn't have a say in following. At this point I am prompted to scroll through images, or 'poses' and encouraged to drag some into my collections. The only thing that stands out is a close-up of a grey t-shirt that says 'F*CK' (but with the U) at which point I'm tempted to create a 'So Subversive' collection just for it. (I don't.) I notice buttons scattered throughout that have a user name and image and they seem to be competing for my attention, so I bite and hit one to see what happens. It brings me to this person's stream and indicates I am now following them. Again, no choice and no prior indication this would happen. This particular Poser has 6646 followers and is following 45 people back. That's not very sociable. At this point I know it's definitely not for me. It hasn't offered anything different from other similar interactive fashion communities I've seen (not that I've seen everything), other than it's the only one that places you exactly where it wants you, rather than let you create your own experience. I'm an adult, I can make my own decisions. But I persevere because this is a review. I hit 'Shop' in the side menu and select a photo of a girl wearing a white outfit. From here I can shop pieces of the outfit and I wind up on the Barneys site looking at a Sophie Hume bag and it's like a breath of fresh air being there. I go back to the outfit page at which point the left menu navigation disappears, I can't figure out how to get off the page and I take that as a sign that I'm allowed to bail.?

My overall impression: If you like looking at style photos of bloggers, celebrities and other fashionistas and don't mind being plunked into an experience that has been quite conspicuously chosen for you, then have a go. You could have fun. One million other people seem to be.?

The Pose app is free and can be downloaded for iPhone, iPod touch and iPad?here

Capture2

The last app I'm reviewing is Bangstyle which I saw on a 'Best Beauty Apps of 2012 list'. I thought it might come in handy for avoiding a repeat of my last salon visit where I tried to describe a very popular colour technique to a colourist who had no clue what I was talking about. (How could she not know what ombre is?!) It's always best to have a photo, you really don't want to assume your stylist knows what you're asking for. (I once wound up with what was essentially a layered bowl cut on top of long hair when I asked for volume. No amount of 'blending' by the salon owner who saw the atrocity and stepped in could salvage it. Don't let this happen to you!)?

Ok, so first you create a profile, which according to the reviews was a prohibitively glitchy process at some point and got the app lots of low ratings. It's not anymore and I was able to sign up quickly. Next I'm taken to the Image Community for Hair page (above left) and have a browse of the styles. There is just one page and when I get to the last one a window pops up telling me it's the last and to go to 'Fresh Pix' to view more. I return to the Image Community and see the Fresh Pix tab at the bottom of the page. The pages do not load quickly which was another gripe users expressed in the reviews. I've waited for at least 10 seconds to be shown a new set of hairstyle photos which seems excruciatingly long for something that's meant to deliver instant gratification. I don't see anything that jumps out so I load more and wait again. It seems lots of users have not tagged their image because I see many labelled 'photo' which I imagine is a default tag. You can share an image or heart it to save it to your inspiration folder within the app which I tried and found easy and straightforward. I decide to look at the Articles tab and surprisingly, I find articles that have absolutely nothing to do with hair! There's one on cameras, an artist who creates illusions using wood, how to bake message into your cakes...then I see the filter for the articles and yes, it covers anything and everything. Is this meant to take the place of glossy magazines in the salon? Instead of being stuck with an old copy of Hello! to thumb through?you read articles on a hairstyle app? Who knows! The My Style feature is where your activity such as saved photos and uploaded pics is organised. There's also a salon locator...still waiting for that to load as I write this... still waiting...I'm glazing over... My phone gave up and went to sleep. After waiting for two minutes I had to quit and start over. I fared no better after a second attempt and now I can't get into anything. Ok! We're back in. Finally. I want to see if I can filter the styles within the Fresh Pix pages so I can look for particular styles I'm interested in. You can't do this on the Image Community page so I'm not sure what the point of it would be unless it features newly added hairstyles? And I'm stuck staring at the swirly circle again. This is a simple app that could be thoroughly checked in just a few minutes so the download time is really frustrating. Ok, at least I'm able to filter styles now, this is where the app becomes useful to me. Or so I thought. I select 'Bangs' and it does nothing. So I try 'Long' and the same thing, nothing. Looking through the list I can see it doesn't have any kind of a colour category which would surely be an essential for people considering a new look? I tried to go back in three more times with no luck. Oh boy. If you were in the salon trying to show a photo from this app you would have one mighty frustrated hairstylist tapping her foot next to you. I bail on it, and I think you know what my final assessment will be.?

My overall impression: Slow loading times and being forced to quit - a third complaint mentioned several times in the reviews - makes it impossible to use this app. What a shame as it may have been useful in the salon. A thorough check of the filter function would hav confirmed that either way.?

The Bangstyle app is free (it would have to be) and is available for iPhone and Android here?if you're still curious.

If you have tried and true suggestions for helpful alternatives please feel free to let us know!?

Source: http://www.theswellelife.com/swelle_life/2013/05/fashion-apps-to-play-with.html

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Mainz University obtains new CRC 'Nanodimensional polymer therapeutics for tumor therapy'

Mainz University obtains new CRC 'Nanodimensional polymer therapeutics for tumor therapy' [ Back to EurekAlert! ] Public release date: 31-May-2013
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Contact: Professor Rudolf Zentel
zentel@uni-mainz.de
49-613-139-20361
Johannes Gutenberg Universitaet Mainz

Mainz chemists and physicians develop nanoparticle-based immunotherapy for cancer

The German Research Foundation (DFG) has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P). Starting in October 2013, the Collaborative Research Center will receive grants totaling approximately EUR 11 million over four years to develop a nanoparticle-based cancer therapy to combat melanoma as an immunogenic tumor model. The Mainz scientists will focus on a form of cancer immunotherapy that is specifically suitable for permanently eliminating minimal residual disease, such as hidden metastases. The new CRC is notable for its interdisciplinary approach: chemists will study the synthetic feasibility and the structure-property relationships of carrier materials, while immunologists and biomedical specialists develop models for the optimal use of such carriers in the form of a new combination therapy for activating the body's immune response against the cancer. The coordinator of the new DFG-funded Collaborative Research Center is Professor Rudolf Zentel from the Institute of Organic Chemistry at Johannes Gutenberg University Mainz. Assistant coordinators are Professor Stephan Grabbe from the Department of Dermatology at the Mainz University Medical Center and Professor Katharina Landfester from the Max Planck Institute for Polymer Research in Mainz. In addition, the Board of Directors will include Professor Detlef Schuppan from the Department of Internal Medicine I at the Mainz University Medical Center and Dr. Mathias Barz from the JGU Institute of Organic Chemistry as a representative of young researchers.

The combination of the expertise of Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research, one of the leading sites for polymer chemistry in Germany, together with the excellent research structure in the area of tumor immunotherapy at the Mainz University Medical Center, will enable the new CRC to conduct research at the broadest level. "This new Collaborative Research Center will bring together these very strong research areas to create new medical challenges for natural scientists as well as to provide medical research with a stronger natural scientific orientation," said the coordinator of the CRC, Professor Rudolf Zentel. "Researchers from the field of chemistry, alongside immunologists and biomedical specialists, will develop novel, multifunctional, nanodimensional therapeutic agents with the aim of releasing agents and combinations of agents in as cell-specific a way as possible, and to also make it possible to make very sensitive agents, such as RNA, therapeutically usable. In an intensively interdisciplinary process, we will combine innovative therapeutic approaches from immunology and oncology with the synthesis of a broad array of well-characterized, suitably functional polymeric nanoparticles with clear physicochemical characterization in the biological environment."

For the chemists, the challenge is to synthesize well-defined polymeric carrier systems and to modify them, render them functional, and to load them with suitable therapeutic agents. Building on these initial synthetic steps, the scientists will go on to test these carrier systems in cross-sectional projects with respect to their interactions in extracellular media, cellular uptake, and distribution in the body. "Our biomedical specialists will then test these systems in combined tumor immunotherapy based on the targeted induction of inflammation in the tumor, stimulation of the immune response, and neutralization of tumor tolerance," said Professor Stephan Grabbe, Director of the Department of Dermatology at the Mainz University Medical Center.

"This Collaborative Research Center is the fruit of decades of excellent research achievements by Mainz scientists in chemistry and medicine and demonstrates the success of building profiles and specialties in science and research at our university," said the President of Johannes Gutenberg University Mainz, Professor Georg Krausch. Mainz has distinguished itself through its many years of successful activity in the field of polymer research and its current work in CRC 625: From single molecules to nanoscale structured materials, Mainz has become renowned for its great expertise in creating and characterizing the physicochemical nature of nanoparticular systems. This makes it possible to create narrowly distributed functional polymer structures and to investigate their aggregate formation in a biological context. In addition, the new CRC will benefit from extensive expertise in the organic chemistry of natural substances, concentrated in the Center for the Synthesis of Natural Products, which is funded by the federal state of Rhineland-Palatinate, BASF and Boehringer Ingelheim and which contributes to the knowledge of linkers and identification structures as well as a radiopharmaceutical division with outstanding chemical processing options, for example in the field of labeling chemistry and in vivo imaging using PET at the JGU Institute of Nuclear Chemistry. The Max Planck Institute for Polymer Research is also a competent partner for the synthesis and characterization of polymeric carriers.

The Mainz University Medical Center has established a specialty area in immunology with experience in immunotherapy as well as a Center for Translational Oncology (TRON) in combination with new spin-off firms, such as GANYMED, which can supply anti-tumor antibodies. Overall, there is a longstanding tradition of basic research in tumor immunology at the Mainz University Medical Center with the development of new concepts in tumor immunotherapy, culminating in clinical trials focused on melanoma, for example, in Collaborative Research Center 432, which concentrates on tumor immunology and experimental therapy. In addition, the Center for Natural Sciences and Medicine, headed by Professor Stephan Grabbe, has encouraged similar kinds of collaboration between medicine and the natural sciences at Johannes Gutenberg University Mainz for more than 30 years.

"The new Collaborative Research Center shows that it makes sense to encourage the development of strong network structures in Mainz and the region. The concept of the CRC is promising because initial successes, specifically in melanoma treatment, have demonstrated that this treatment concept may contribute to making it possible in the future to successfully treat cancers that are now incurable," emphasized Professor Frstermann, Chief Scientific Officer of the Mainz University Medical Center.

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Mainz University obtains new CRC 'Nanodimensional polymer therapeutics for tumor therapy' [ Back to EurekAlert! ] Public release date: 31-May-2013
[ | E-mail | Share Share ]

Contact: Professor Rudolf Zentel
zentel@uni-mainz.de
49-613-139-20361
Johannes Gutenberg Universitaet Mainz

Mainz chemists and physicians develop nanoparticle-based immunotherapy for cancer

The German Research Foundation (DFG) has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P). Starting in October 2013, the Collaborative Research Center will receive grants totaling approximately EUR 11 million over four years to develop a nanoparticle-based cancer therapy to combat melanoma as an immunogenic tumor model. The Mainz scientists will focus on a form of cancer immunotherapy that is specifically suitable for permanently eliminating minimal residual disease, such as hidden metastases. The new CRC is notable for its interdisciplinary approach: chemists will study the synthetic feasibility and the structure-property relationships of carrier materials, while immunologists and biomedical specialists develop models for the optimal use of such carriers in the form of a new combination therapy for activating the body's immune response against the cancer. The coordinator of the new DFG-funded Collaborative Research Center is Professor Rudolf Zentel from the Institute of Organic Chemistry at Johannes Gutenberg University Mainz. Assistant coordinators are Professor Stephan Grabbe from the Department of Dermatology at the Mainz University Medical Center and Professor Katharina Landfester from the Max Planck Institute for Polymer Research in Mainz. In addition, the Board of Directors will include Professor Detlef Schuppan from the Department of Internal Medicine I at the Mainz University Medical Center and Dr. Mathias Barz from the JGU Institute of Organic Chemistry as a representative of young researchers.

The combination of the expertise of Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research, one of the leading sites for polymer chemistry in Germany, together with the excellent research structure in the area of tumor immunotherapy at the Mainz University Medical Center, will enable the new CRC to conduct research at the broadest level. "This new Collaborative Research Center will bring together these very strong research areas to create new medical challenges for natural scientists as well as to provide medical research with a stronger natural scientific orientation," said the coordinator of the CRC, Professor Rudolf Zentel. "Researchers from the field of chemistry, alongside immunologists and biomedical specialists, will develop novel, multifunctional, nanodimensional therapeutic agents with the aim of releasing agents and combinations of agents in as cell-specific a way as possible, and to also make it possible to make very sensitive agents, such as RNA, therapeutically usable. In an intensively interdisciplinary process, we will combine innovative therapeutic approaches from immunology and oncology with the synthesis of a broad array of well-characterized, suitably functional polymeric nanoparticles with clear physicochemical characterization in the biological environment."

For the chemists, the challenge is to synthesize well-defined polymeric carrier systems and to modify them, render them functional, and to load them with suitable therapeutic agents. Building on these initial synthetic steps, the scientists will go on to test these carrier systems in cross-sectional projects with respect to their interactions in extracellular media, cellular uptake, and distribution in the body. "Our biomedical specialists will then test these systems in combined tumor immunotherapy based on the targeted induction of inflammation in the tumor, stimulation of the immune response, and neutralization of tumor tolerance," said Professor Stephan Grabbe, Director of the Department of Dermatology at the Mainz University Medical Center.

"This Collaborative Research Center is the fruit of decades of excellent research achievements by Mainz scientists in chemistry and medicine and demonstrates the success of building profiles and specialties in science and research at our university," said the President of Johannes Gutenberg University Mainz, Professor Georg Krausch. Mainz has distinguished itself through its many years of successful activity in the field of polymer research and its current work in CRC 625: From single molecules to nanoscale structured materials, Mainz has become renowned for its great expertise in creating and characterizing the physicochemical nature of nanoparticular systems. This makes it possible to create narrowly distributed functional polymer structures and to investigate their aggregate formation in a biological context. In addition, the new CRC will benefit from extensive expertise in the organic chemistry of natural substances, concentrated in the Center for the Synthesis of Natural Products, which is funded by the federal state of Rhineland-Palatinate, BASF and Boehringer Ingelheim and which contributes to the knowledge of linkers and identification structures as well as a radiopharmaceutical division with outstanding chemical processing options, for example in the field of labeling chemistry and in vivo imaging using PET at the JGU Institute of Nuclear Chemistry. The Max Planck Institute for Polymer Research is also a competent partner for the synthesis and characterization of polymeric carriers.

The Mainz University Medical Center has established a specialty area in immunology with experience in immunotherapy as well as a Center for Translational Oncology (TRON) in combination with new spin-off firms, such as GANYMED, which can supply anti-tumor antibodies. Overall, there is a longstanding tradition of basic research in tumor immunology at the Mainz University Medical Center with the development of new concepts in tumor immunotherapy, culminating in clinical trials focused on melanoma, for example, in Collaborative Research Center 432, which concentrates on tumor immunology and experimental therapy. In addition, the Center for Natural Sciences and Medicine, headed by Professor Stephan Grabbe, has encouraged similar kinds of collaboration between medicine and the natural sciences at Johannes Gutenberg University Mainz for more than 30 years.

"The new Collaborative Research Center shows that it makes sense to encourage the development of strong network structures in Mainz and the region. The concept of the CRC is promising because initial successes, specifically in melanoma treatment, have demonstrated that this treatment concept may contribute to making it possible in the future to successfully treat cancers that are now incurable," emphasized Professor Frstermann, Chief Scientific Officer of the Mainz University Medical Center.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/jgum-muo053113.php

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'Truly Boston Strong' at show for marathon victims

Boston Marathon bombing victim CVictoria McGrath, 20, center, thanks people who help her when she was injured and help her recovery during the Boston Strong Concert: An Evening of Support and Celebration at the TD Garden on Thursday, May 30, 2013 in Boston. (Photo by Bizuayehu Tesfaye/Invision/AP)

Boston Marathon bombing victim CVictoria McGrath, 20, center, thanks people who help her when she was injured and help her recovery during the Boston Strong Concert: An Evening of Support and Celebration at the TD Garden on Thursday, May 30, 2013 in Boston. (Photo by Bizuayehu Tesfaye/Invision/AP)

Steven Tyler, lead singer of American rock band Aerosmith performs on Saturday, May 25, 2013 in Singapore during the inaugural Social Star Awards concert.(AP Photo/Wong Maye-E)

BOSTON (AP) ? City residents rocked Thursday at a benefit concert for victims of the deadly Boston Marathon bombing, jamming to songs from the Dropkick Murphys, Boston and other musical acts and even laughing at a joke about the capture of a bombing suspect.

The Boston Strong Concert kicked off with the rock band Boston playing songs including its 1970s hit "More Than a Feeling."

"Tonight, we are all Boston," lead singer Tommy DeCarlo declared to a crowd of thousands of people, including victims and first responders, at the TD Garden.

The Dropkick Murphys, whose rousing rendition of "I'm Shipping Up to Boston" was a crowd favorite, were introduced by former New England Patriots player Joe Andruzzi, who was watching the April 15 marathon when the bombs went off and helped victims at the scene.

"When I looked around that day, the image that's in my mind is seeing more people run to the site than run away," Andruzzi said. "That is truly Boston Strong."

Concertgoer Harry Donovan said Boston residents weren't going to let "any violence, any hatred bring this town down."

"This city took a hit, there's no doubt, but Boston, like a lot of other cities, is resilient," said Donovan, of nearby Wellesley.

Bombing victim Jeff Bauman, who lost his legs in one of the blasts and was led from the scene in a wheelchair, also attended and smiled on a massive television screen.

As the members of 1990s Boston boy band New Kids on the Block took the stage to perform, member Joey McIntyre, who had finished running in the marathon 10 minutes before the bombs went off, choked up.

"I happened to be on a bench in Copley Plaza, Copley Square," McIntyre said, "but I don't care where you were that day, because this happened to all of us."

Surprise guests Boyz II Men joined NKOTB on stage for "One Sweet Day" in tribute to those who lost their lives in the attack.

Other acts taking part in the benefit show included country singer Jason Aldean and comedian Steven Wright. James Taylor performed "Sweet Baby James" with Carole King on piano.

More than once, the words "Boston Strong" were met with cheers and fist pumps from the energetic crowd.

"I love that phrase," enthused Boston comic Lenny Clarke, whose cathartic set featured a foul-mouthed, one-man reenactment of the capture of bombing suspect Dzhokhar Tsarnaev. "You know what I don't love? 'Shelter in place.'"

Boston area residents were locked down, told to shelter in place, a few days after the bombing while authorities searched for Tsarnaev, who was found hiding in a boat in a backyard in suburban Watertown. Tsarnaev's older brother, Tamerlan Tsarnaev, had died after a shootout with police.

The suspects, ethnic Chechens from Russia, are accused of setting off two pressure cooker bombs packed with shrapnel near the marathon's finish line, killing three people and injuring more than 260 others. Their mother has insisted they are innocent.

Concert proceeds will go to One Fund Boston, the compensation fund established by Gov. Deval Patrick and Mayor Thomas Menino to help bombing victims.

The amount of money raised by the concert won't be available until next week, a spokesman for the event's producer said. Ticket prices for the sold-out show ranged from $35 to close to $300.

It was a night of joy, tears, laughter and standing ovations, but co-organizer and NKOTB member Donnie Wahlberg said the artists on stage were not the true stars.

"You deserve the credit," the Dorchester native told the crowd. "I think we've shown the world in the last few months what many in Boston have already known, that we are not just one of the greatest cities in the world, we are one of the greatest families in the world."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-05-30-Boston%20Marathon-Concert/id-6f01386f2dd7466195a1ed60b52ce95f

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Despite clock issues, Indiana Pacers outlast Heat in Game 4 of NBA Eastern finals

The Indiana Pacers got 23 points and 12 rebounds from Roy Hibbert and 20 points from Lance Stephenson to defeat the Miami Heat, 99-92, in Indianapolis to knot their best-of-seven NBA Eastern Conference final at two games apiece. It was also Miami?s first road loss of the postseason.

David West contributed 14 points and 12 rebounds of his own in taking the Pacers? inside offensive game straight to Miami?s ?bigs? ? Chris Bosh, Chris Andersen and Udonis Haslem. The Pacers? driving inside, largely by the trio of Stephenson, Paul George and George Hill, yielded 50 points in the paint to the Heat?s 32 ? along with a robust 19 second-chance points. Indiana also fought a decisive battle on the glass, out-rebounding the Heat 49-30, with 35 of those coming off the defensive boards.

RECOMMENDED: Retired NBA Finals MVPs: What are they doing now?

Hibbert has said in interviews that he may not block most shots, but that he ?changes? opponents? shots ? taking them out of their comfort zones. Nowhere was this more evident than Tuesday night. Indiana shot 35-of-70 from the floor (50%) against Miami?s 39% - with LeBron James (8-18), Dwyane Wade (5-15) and Mario Chalmers (6-14) often feeling the pressure inside from Hibbert and West.

The Pacers got five players into double figures, with Hibbert, Stephenson and West being joined by George Hill with 19 (in addition to 6 assists), and Paul George?s 12. The Heat had four players in double-digits, including James with 24 points on 4-7 from beyond the three-point arc, Chalmers with 20, Wade with 16 points to go with 6 assists, and Ray Allen, who had 11 points, including two timely three-pointers. He also grabbed 7 rebounds.

A refreshing development for the Heat is that they?ve managed to control the ball better of late. In the first two games, they committed a total of 34 turnovers; in the last two, only 11. But offsetting that was the impressive 30 personal fouls they amassed in Game 4 ? including a key one on James with time running out.

There were several instances where Indiana seemed ready to fold the tent ? no one more glaring than early in the fourth quarter. With the Pacers up 81-72, Indiana was whistled for a 24-second shot clock violation after a Tyler Hansbrough layup was disallowed because the clock did not reset after Hibbert's initial shot attempt had obviously bounced off the rim. The officials did not review it, and Indiana went into a tailspin by allowing the Heat go on a 14-2 run to take the lead, 86-83.

But the Pacers regained momentum in time to close out the game with their own 16-6 scoring binge. A controversial call on a defensive screen in the last 56 seconds had Miami?s James leaving the game with his sixth foul, and Indiana was able to wait out the clock by hitting free throws. The setting now shifts back to Miami for Game 5 on Thursday.

Related stories

Read this story at csmonitor.com

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Source: http://news.yahoo.com/despite-clock-issues-indiana-pacers-outlast-heat-game-160823309.html

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Thursday 30 May 2013

Academic Life in Emergency Medicine: Out-of-Hospital Cardiac ...

Worldwide, death from cardiac arrest in the out-of-hospital setting remains the leading cause of mortality. Focuses have aimed at improving bystander CPR, public access to AEDs, minimizing chest compression interruptions, and decreasing the emphasis on advanced airway management. This latter concept has become so important that the AHA/ASA have now changed their ?ABC? philosophy to ?CAB.? Below is the review of the literature that has changed this philosophy.

Does Prehospital Intubation Attempts Affect Survival to Hospital Discharge in Out-of-Hospital Cardiac Arrest (OHCA)?


  • Retrospective study design at single site (Mecklenbeurg County, NC)
  • 1,142 cardiac arrests
Primary outcomes:
  • Pre-hospital return of spontaneous circulation (ROSC)
  • Survival to hospital discharge
Descriptive data:
  • 697/1142 (61%) of patients were male
  • 619/1142 (54.2%) of patients were Caucasian
  • 302/1142 (25.5%) had VF/VT arrest
  • 142/1142 (12.8%) witnessed by EMS or first responders
  • 299/1142 (26.2%) had pre-hospital ROSC
Results:
  • Pre-hospital endotracheal intubation (ETI) vs NO ETI: 25.3% vs 45.3% with pre-hospital ROSC?
  • 118/299 (39.5%) of patients with ROSC were discharged alive
  • ETI attempts was a self reported variable
  • Some outcome data from the hospitals was missing
Conclusions: There is a NEGATIVE association between pre-hospital ETI attempts and survival from OHCA.

Does Prehospital Intubation Attempts Affect Survival and Neurologic Outcome in Out-of-Hospital Cardiac Arrest (OHCA)?



  • Prospective, nationwide, population-based study using all-Japan Utstein Registry
  • 649,654 adults in Japan with OHCA
Primary outcome:
  • Favorable neurological outcome 1 month after OHCA
Descriptive data:
  • 367,837/649,359 (57%) underwent BVM
  • 281,522/649,359 (43%) underwent advanced airway management
  • Overall rate of ROSC 6.5%
  • Overall rate of 1 month survival 4.7%
  • Overall rate of favorable neurologic outcome 2.2%
Results: Looking at?ETI vs supraglottic airway vs BVM -
  • Favorable neurological outcome: 1.0%, 1.1%, and 2.9%, respectively
  • OR for favorable neurological outcome: 0.41, 0.38, 0.38, respectively

  • Observational study
  • Absence of information regarding the process of intubation
  • Japanese population only
Conclusion: In OHCA, advanced airway (ETI or supraglottic airway) was independently associated with a DECREASED neurologically favorable outcome compared to conventional BVM.

BOTTOM LINE: Pre-hospital advanced airway WORSENS survival and neurologic outcome in OHCA